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VERSION:2.0
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CALSCALE:GREGORIAN
X-WR-CALNAME:BME Seminar: Adam Feinberg\, PhD
X-WR-TIMEZONE:Central Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260721T173551Z
UID:tag:localist.com\,2008:EventInstance_47003006566204
DTSTART:20241205T160000Z
DTEND:20241205T170000Z
DESCRIPTION:Presenting on "3D Bioprinting Human Tissues and the Path Toward
 s Translation".\n\nAdam W. Feinberg\, PhD\, Professor of Biomedical Engine
 ering and Materials Science and Engineering at Carnegie Mellon University 
 will speak on Thursday\, December\, 5\, 2024 at 10:00 am CT in Whitaker 21
 8.\n\nRegistration to attend virtually is required. Please register here.\
 n\nAbstract: Over the past decade\, 3D bioprinting has rapidly expanded fr
 om a niche technology and into a versatile platform for fabricating tissue
 s with complex geometries and features ranging from the cellular to organ 
 length scales. Recent advances include engineering the 3D cell microenviro
 nment\, hierarchical vascular networks in thick tissue constructs and rege
 nerative tissue scaffolds implanted in animal models and human patients. H
 owever\, there remain a number of disadvantages with current approaches\, 
 and the need to understand how we can improve the structure and function o
 f the engineered tissue constructs. To address this\, we have developed no
 vel biofabrication approaches focused on building extracellular matrix (EC
 M) scaffolds that mimic the structure and composition of the heart and oth
 er tissues and organs. Termed Freeform Reversible Embedding of Suspended H
 ydrogels (FRESH)\, we can 3D bioprint collagen\, fibrin\, decellularized E
 CM\, growth factors\, and a wide range of cell types into complex 3D archi
 tectures. This includes using FRESH to create large\, organ-scale construc
 ts based on patient-specific MRI scans that incorporate functional arterie
 s and valves within full-size\, whole hearts. Ongoing work is focused on c
 ellularizing these constructs with human iPSC-derived cardiomyocytes to cr
 eate beating cardiac tissues and extending these approaches to additional 
 tissue and organ systems for in vitro disease modeling and in vivo regener
 ation.
GEO:38.649125;-90.303135
LOCATION:Uncas A. Whitaker Hall\, 218
SUMMARY:BME Seminar: Adam Feinberg\, PhD
URL;VALUE=URI:https://happenings.washu.edu/event/bme-seminar-adam-feinberg-
 phd
CATEGORIES:Seminar/Colloquia
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