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Electrical & Systems Engineering Seminar | Yang Liu

Friday, December 5, 2025 10 AM to 11 AM

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Yang Liu Professor of Bioengineering & Electrical and Computer Engineering University of Illinois Urbana-Champaign
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About this Event

Preston M. Green Hall, Rodin Auditorium room 0120 View map

135 N Skinker Blvd, St. Louis, MO 63112, USA

#ESE, #ImagingScience
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Illuminating Structure and Dynamics Across Scales for Precision Medicine

Advances in optical imaging are transforming how we study and diagnose disease by connecting molecular architecture with tissue microenvironment in a quantitative, scalable manner across space and time. My group develops optical microscopy technologies that integrate quantitative phase imaging, super-resolution microscopy, and mesoscale spatial mapping to capture structural dynamics and molecular information across wide fields of view. We apply these platforms in clinically relevant contexts to identify distinct epigenetic states associated with cancer progression, autoimmune disease, and therapeutic resistance. I will discuss our recent engineering efforts that extend super-resolution imaging to probe chromatin organization and molecular architecture underlying disease pathogenesis. I will also describe the development of label-free and multimodal imaging workflows that reveal spatial and morphological signatures predictive of treatment response. Together, these integrative imaging frameworks establish a quantitative link between nanoscale molecular structure, mesoscale tissue organization, and clinical phenotypes, advancing optical imaging toward translational and precision medicine. 

Event Details

Event Type

Lectures & Presentations Seminar/Colloquia

Schools

McKelvey School of Engineering

Topic

Science & Technology

Department

Electrical & Systems Engineering, Imaging Science

Hashtag

#ESE, #ImagingScience

Event Contact

Matthew Lew

Speaker Information

Yang Liu

Professor of Bioengineering and Electrical & Computer Engineering

Deputy Director of the Center for Label-free Imaging and Multiscale Biophotonics (CLIMB)

University of Illinois Urbana-Champaign

 

Dr. Yang Liu is a Professor of Bioengineering and Electrical & Computer Engineering, and Deputy Director of the NIH-funded P41 Center for Label-free Imaging and Multiscale Biophotonics (CLIMB) at the University of Illinois Urbana-Champaign. Dr. Liu holds a PhD in Biomedical Engineering from Northwestern University. Dr. Liu’s research focuses on developing multiscale, multimodal optical imaging technologies that bridge molecular, cellular, and tissue scales to address fundamental biological questions and clinical challenges in cancer and inflammation. Her work bridges imaging technology development and biological discovery, bringing together researchers across engineering, biology, and medicine to translate advanced imaging technologies into practical tools for disease diagnosis, patient stratification, and spatial profiling of therapeutic response. Her research has been continuously supported by the National Institutes of Health for nearly two decades. Dr. Liu has authored 100 peer-reviewed publications and holds 11 U.S. patents. She is an elected Fellow of both SPIE and Optica.

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